{"id":720,"date":"2019-01-11T21:22:36","date_gmt":"2019-01-11T21:22:36","guid":{"rendered":"http:\/\/protobiology.org\/wp3\/?p=720"},"modified":"2025-08-27T00:53:59","modified_gmt":"2025-08-27T00:53:59","slug":"introduction","status":"publish","type":"post","link":"http:\/\/protobiology.org\/wp3\/2019\/01\/11\/introduction\/","title":{"rendered":"Introduction"},"content":{"rendered":"<p><a class=\"bookmark\" name=\"introductions\"><\/a><\/p>\n<h1>Synthetic cells 101<\/h1>\n<p><strong>TED talk on synthetic life<\/strong><br \/>\nKate presented concept of building synthetic minimal cells, with its biotechnological, biomedical and basic science implications, in a <a href=\"https:\/\/www.youtube.com\/watch?v=y8ip1mQovVI\" target=\"_blank\" rel=\"noopener\"> TEDx talk <\/a>. <\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/www.youtube.com\/embed\/y8ip1mQovVI\" width=\"380\" height=\"213\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Selected editorials and popular audience owerviews<\/strong><\/p>\n<p>The effort towards building life in the lab and elucidating the origin and earliest evolution of life has always been receiving interest from broad audience.<\/p>\n<p>STAT magazine published nice overview of efforts to build artificial life, <a href=\"https:\/\/www.statnews.com\/2017\/07\/28\/cell-build-from-scratch\/\" target=\"_blank\" rel=\"noopener\">From chemicals to life: Scientists try to build cells from scratch<\/a><a href=\"https:\/\/www.statnews.com\/2017\/07\/28\/cell-build-from-scratch\/\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-725 size-full\" src=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2019\/01\/stat.jpg\" alt=\"prototyping biology\" width=\"145\" height=\"82\" \/><\/a>.<\/p>\n<p>This great editorial in Science is <a href=\"http:\/\/science.sciencemag.org\/content\/362\/6417\/877\" target=\"_blank\" rel=\"noopener\"> intorducing new, exciting paper and highlighting interesting aspects of building synthetic cells.<\/a><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-018-07289-x\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-609\" src=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612-200x136.jpg\" alt=\"prototyping biology\" width=\"150\" height=\"102\" srcset=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612-200x136.jpg 200w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612-150x102.jpg 150w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612-768x522.jpg 768w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612-1024x696.jpg 1024w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/d41586-018-07289-x_16251612.jpg 1172w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><br \/>\nExcellen editorial in Nature, <a href=\"https:\/\/www.nature.com\/articles\/d41586-018-07289-x\" target=\"_blank\" rel=\"noopener\">describing rationale of engineering synthetic life, and the most common approaches to various problems we&#8217;re facing en route to a synthetic cell. <br \/>\n<\/a> And <a href=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2018\/11\/nature_synbiosyntheticcelldesigns.pdf\">local copy pdf<\/a><\/p>\n<p>Kate&#8217;s article on <a href=\"https:\/\/medium.com\/@TEDxBeaconStreet\/why-should-we-personalize-medicine-d4f7018dfe11\" target=\"_blank\" rel=\"noopener\">personalised medicine using synthetic cell technologies<\/a><\/p>\n<p>iBiology synthetic cell talks:<br \/>\n<a href=\"https:\/\/www.ibiology.org\/bioengineering\/synthetic-cells\/#part-1\" target=\"_blank\" rel=\"noopener\"> Part 1: Synthetic Cells: Building Life to Understand It<\/a><a href=\"https:\/\/www.ibiology.org\/bioengineering\/synthetic-cells\/#part-1\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1426 size-thumbnail\" src=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p1-150x87.jpg\" alt=\"prototyping biology\" width=\"150\" height=\"87\" srcset=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p1-150x87.jpg 150w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p1-200x117.jpg 200w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p1.jpg 271w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><br \/>\n<a href=\"https:\/\/www.ibiology.org\/bioengineering\/synthetic-cells\/#part-2\" target=\"_blank\" rel=\"noopener\"> Part 2: Synthetic Cells: Approach and Applications<\/a><a href=\"https:\/\/www.ibiology.org\/bioengineering\/synthetic-cells\/#part-2\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1427 size-thumbnail\" src=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p2-150x87.jpg\" alt=\"prototyping biology\" width=\"150\" height=\"87\" srcset=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p2-150x87.jpg 150w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p2-200x116.jpg 200w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2021\/11\/p2.jpg 266w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/p>\n<p>Some examples of the astrobiology focus: a review detailing our work on RNA replication in protocells: Angewandte Chemie International Edtion <strong>Citric Acid and the RNA World<\/strong> 2014, 53, 5245 &#8211; 5247, <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201400847\/abstract\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2014_angew_review.pdf\">local copy pdf<\/a>)<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-244\" src=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2017\/04\/600x600bb-150x150.jpg\" alt=\"prototyping biology\" width=\"80\" height=\"80\" srcset=\"http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2017\/04\/600x600bb-150x150.jpg 150w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2017\/04\/600x600bb-200x200.jpg 200w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2017\/04\/600x600bb-100x100.jpg 100w, http:\/\/protobiology.org\/wp3\/wp-content\/uploads\/2017\/04\/600x600bb.jpg 600w\" sizes=\"auto, (max-width: 80px) 100vw, 80px\" \/>Aaron and Kate did NPR podcast on the origin of life &#8211; <a href=\"http:\/\/www.brainson.org\/what-was-the-first-life-on-earth\/\" target=\"_blank\" rel=\"noopener noreferrer\">Brains on!<\/a><\/p>\n<p>Our work on protocells have been featured in science news outlets and editorials, including:<br \/>\nScience Focus: Robert Service, <strong>The Life Force<\/strong>, <a href=\"https:\/\/www.sciencemag.org\/content\/342\/6162\/1032.short\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2013_science_editorial.pdf\">local copy pdf<\/a>)<br \/>\nBioTechniques: <strong>How Cellular Life Evolved<\/strong> 06 Jan 2014 <a href=\"http:\/\/www.biotechniques.com\/news\/How-Cellular-Life-Evolved\/biotechniques-349115.html\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2014_biotechniques_editorial.pdf\">local copy pdf<\/a>)<br \/>\nScience News: <strong>To cook up life, just add citrate<\/strong> 185(1):15 <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/scin.5591850111\/abstract\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2014_sciencenews_citrate.pdf\" target=\"_blank\" rel=\"noopener\">local copy pdf<\/a>)<br \/>\nScience Daily: <strong>Researchers find missing component in effort to create primitive, synthetic cells<\/strong>, <a href=\"http:\/\/www.sciencedaily.com\/releases\/2013\/11\/131128141401.htm\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2013_ScienceDaily_citrate.pdf\">local copy pdf<\/a>)<br \/>\nChemical &amp; Engineering News: <strong>Lab-Made Protocells Show Hints Of Evolution<\/strong>, 91(21), 2013<br \/>\nThe Panda&#8217;s Thumb: <strong>New Szostak protocell is closest approximation to origin of life and Darwinian evolution so far<\/strong>, <a href=\"http:\/\/pandasthumb.org\/archives\/2013\/12\/new-szostak-pro.html\" target=\"_blank\" rel=\"noopener\">external link<\/a> (<a href=\"http:\/\/www.protobiology.org\/reprints\/2013_pandas_thumb_citrate.pdf\">local copy pdf<\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Synthetic cells 101 TED talk on synthetic life Kate presented concept of building synthetic minimal cells, with its biotechnological, biomedical and basic science implications, in a TEDx talk . &nbsp; Selected editorials and popular audience owerviews The effort towards building life in the lab and elucidating the origin and earliest evolution of life has always &hellip; <\/p>\n<p class=\"link-more\"><a href=\"http:\/\/protobiology.org\/wp3\/2019\/01\/11\/introduction\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Introduction&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-720","post","type-post","status-publish","format-standard","hentry","category-static"],"_links":{"self":[{"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/posts\/720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/comments?post=720"}],"version-history":[{"count":27,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/posts\/720\/revisions"}],"predecessor-version":[{"id":2131,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/posts\/720\/revisions\/2131"}],"wp:attachment":[{"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/media?parent=720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/categories?post=720"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/protobiology.org\/wp3\/wp-json\/wp\/v2\/tags?post=720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}